Remote Biomarker Collection in the COVID-19 Era: Strategies for respondent self-collection
Remote Biomarker Collection in the COVID-19 Era: Strategies for respondent self-collection
Agenda
- Introduction & Background
- Overview of remote blood collection strategies
- Dried blood spots (mailable self-draw kits; HemaSpot HF/SE/HD)
- Microfluidic samplers (Tasso OnDemand, TAP 2nd Gen)
- Logistics & infrastructure (mailing/transport, self-collection instructions/videos, participant support, regulatory issues, logistics services)
- Optimizing self-collected blood samples
- Sample collection protocols, with tips & tricks for both DBS & microfluidics
- Customized instruction videos, Zoom “call centers”/”office hours”
- Analytic performance: what works, and what doesn’t
- Correspondence of DBS / microfluidic samples to venipuncture “gold standard”
- Issues to manage (sample volume, humidity, temperature)
- Interpretive caveats (SNR/power adjustment, LLD, fragile/untrustworthy analytes, venous vs capillary blood)
- Experienced assay labs (volume, system-level QC)
- Temperature control
- Cold-chain maintenance (Health & Retirement Study salivary antibody example)
- Logistics services (e.g., UPS Healthcare)
- Q&A
- Adjourn