Agenda

Welcome Remarks (Crimmins, Faul, Mitchell)

Remarks from NIA (Braudt)

Epigenetic Measurement and Methods

• Epigenetic scores of accelerated pubertal development are associated with aging outcomes among older adults (Wu)
• A DNA methylation biomarker of Intrinsic Capacity (Sugden)
• FraminghamPACE: A new DNA methylation biomarker of the Pace of Aging (Marella)

Long Read Sequencing

• Long read sequencing enables coordinated multi-scaled data analysis from large population studies: Findings from High School and Beyond and the Health and Retirement Study (Zhu)

Pilot Presentation

• Establish the Feasibility of Implementing Personal Wearable Air Quality Monitors with Accelerometery to Examine Associations of Air Pollution and Movement Behaviours with Day-To-Day Cardiovascular Function in Older Adults (Bloomberg)

Updates from Network Labs

• Advanced Research and Diagnostic Laboratory (Thyagarajan)
• Kobor Lab (Brewis)
• Department of Laboratory Medicine (Potter & Cofferen)
• Laboratory for Human Biology Research (McDade)
• BioSpecimen Lab (Kumpelis)

Proteomics

• FFCW Olink Inflammation Panel Exploration (Mitchell)

New Measures and Measurement Reliability

• Short-Term Reliability of Anthropometric, Cardiovascular, and Biomarker Data in Wave VI of Add Health: An IntraIndividual Variation Sub-Study (Hummer)
• Measurement of intestinal fatty-acid binding protein (IFABP) and other intestinal barrier function biomarkers in dried blood spots using ELISA (Kim)
• Defining Menopause in Midlife: Measurement Challenges in Population-Based Studies (McCoy)

Biomarkers of Cognitive Function and Decline

• A New Frontier in ADRD Research in Low-Income Countries: Using Dried Plasma Spots (DPS) for Dementia Biomarkers in Population-Based Aging Surveys (Kohler)
• DBS-based Biomarkers of Neurodegeneration predict Cognitive Decline and Dementia Seven Years Ahead in a Large Population-Based Sample (Boersch-Supan)
• The Salivary Microbiome and Cognitive Function (Warren)

Study and Network Updates

• Center on Biodemography and Population Health (CBPH) Population Study-Lab Partnerships Meeting (Ailshire)
• Colombian Study of Aging (COSA) (Ailshire)
• NIH Animal Models for the Social Dimensions of Health and Aging Research Network (Harris)
• The National Couples’ Health and Time Stress Biology Study (NCHAT-BIO) – Wave 1 Methodology Report and Wave 3 Preview (Christian)

Closing Remarks (Crimmins, Faul, Mitchell)

Poster Presentations

• Methodological Approaches to Biological Age Estimation using Blood Biomarkers: Evidence from SHARE (Paccagnella)
• Pooling Cohorts Across the Life Course to Investigate Early-Life Determinants of Health Outcomes in Later-Life (Kezios)